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Allele : Rag2<tm1.1Mss> recombination activating gene 2; targeted mutation 1.1, Mark S Schlissel

Primary Identifier  MGI:5002798 Allele Type  Targeted
Attribute String  Hypomorph, Inserted expressed sequence Gene  Rag2
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A cDNA encoding exons 1-383 and an engineered stop codon at position 384 and a floxed neomycin selection cassette replaced the endogenous coding sequence. The resulting allele lacks the sequence encoding amino acids 384-527 of the intact protein. The selection cassette was subsequently removed by cre excision.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Rag2<c>,
  • Rag2<CORE>,
  • Rag2<c>,
  • Rag2<CORE>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

9 Publication categories