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Allele : Trp53<tm4Glo> transformation related protein 53; targeted mutation 4, Guillermina Lozano

Primary Identifier  MGI:5000493 Allele Type  Targeted
Attribute String  Hypomorph Gene  Trp53
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site flanked neomycin resistance gene cassette was inserted into intron 4. Reduced protein expression was confirmed by western blot analysis on doxorubicin-treated mouse embryonic stem cells. This allele is hypomorphic.
  • mutations:
  • Insertion
  • synonyms:
  • p53<neo>,
  • p53<neo>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories