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Allele : Tg(Hmgcr-PSEN1*M146L)#Lpr transgene insertion, Laurent Pradier
Primary Identifier  MGI:5003458 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(Hmgcr-PSEN1*M146L)#Lpr
Strain of Origin  CBA x C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  The murine Hmgcr promoter drives expression a human PSEN1 cDNA, which includes the intron between exons 4 and 5 and carries a methionine to leucine substitution at amino acid 146 (M146L).
  • mutations:
  • Insertion
  • synonyms:
  • HMG-PS1M146L,
  • HMG-PS1M146L
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

25 Publication categories





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