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Allele : Col1a1<tm7(tetO-HIST1H2BJ/GFP)Jae> collagen, type I, alpha 1; targeted mutation 7, Rudolf Jaenisch
Primary Identifier  MGI:5007779 Allele Type  Targeted
Attribute String  Humanized sequence, Inducible, Inserted expressed sequence, RMCE-ready Gene  Col1a1
Transmission  Germline Strain of Origin  (C57BL/6 x 129S4/SvJae)F1
Induced With  doxycycline/tetracycline Is Recombinase  false
Is Wild Type  false
description  The allele was made in KH2 cells that carry Gt(ROSA)26Sortm1(rtTA*M2)Jae and Col1a1tm13(neo/hygro*)Jae (J:159351). This allele was generated with Col1a1tm13(neo/hygro*)Jae.
molecularNote  RMCE on KH2 cells inserted a cassette that contains a cDNA encoding human H2B (HIST1H2BJ) tagged at its carboxyl terminus with DNA encoding codon-optimized enhanced GFP under the transcriptional control of a tetracycline-dependent minimal CMV promoter into the 3'UTR.
  • mutations:
  • Insertion
  • synonyms:
  • TetOP-H2B-GFP,
  • TetOP-H2B-GFP
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

44 Publication categories





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