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Allele : Notch1<tm4(cre)Rko> notch 1; targeted mutation 4, Raphael Kopan

Primary Identifier  MGI:5009236 Allele Type  Targeted
Attribute String  Recombinase Gene  Notch1
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  true Is Wild Type  false
molecularNote  The Notch1 intracellular domain (IC) is replaced by the cre recombinase sequence and includes the SV40 3' UTR polyA signal while introducing a single nucleotide variation (SNV) at C5178A to facilitate genotyping. This allele does not have the 6xMyc tag present in the Notch1tm3(cre)Rko allele, and displays enhanced activity relative to that allele.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • NIP::Cre<HI>,
  • N1::Cre<hi>,
  • NIP::Cre<HI>,
  • Notch1::cre<Hi>,
  • N1::Cre<hi>,
  • Notch1::cre<Hi>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

1 Driven By

Trail: Allele

11 Publication categories

Trail: Allele