| Primary Identifier | MGI:5009328 | Allele Type | Transgenic |
| Attribute String | Inducible, Recombinase | Gene | Et(cre/ERT2)25175Rdav |
| Strain of Origin | C57BL/6J | Induced With | tamoxifen |
| Is Recombinase | true | Is Wild Type | false |
| Project Collection | Neuroscience Blueprint cre |
| molecularNote | The Pak7-Cre-ERT2-bGHpA transgene was designed with a mouse p21 protein (Cdc42/Rac)-activated kinase 7 (Pak7) minimal promoter (-77 to +277), a rabbit beta globin intron (650 bp), a CreERT2 fusion gene (Cre-ERT2), and a bovine growth hormone polyA signal. This transgene was injected into C57BL/6J mouse embryos. To establish founder line 25175, founder mice (F0) were bred to B6.R26-lacZ mutant mice (Gt(ROSA)26Sortm1Sor mutant mice backcrossed to C57BL/6N or C57BL/6J for at least 10 generations. CreERT2-positive::lacZ-positive transgenic mice (F1) were bred to C57BL/6 mice. |
