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Allele : Et(cre/ERT2)25175Rdav enhancer trap 25175, Ron Davis
Primary Identifier  MGI:5009328 Allele Type  Transgenic
Attribute String  Inducible, Recombinase Gene  Et(cre/ERT2)25175Rdav
Strain of Origin  C57BL/6J Induced With  tamoxifen
Is Recombinase  true Is Wild Type  false
Project Collection  Neuroscience Blueprint cre
molecularNote  The Pak7-Cre-ERT2-bGHpA transgene was designed with a mouse p21 protein (Cdc42/Rac)-activated kinase 7 (Pak7) minimal promoter (-77 to +277), a rabbit beta globin intron (650 bp), a CreERT2 fusion gene (Cre-ERT2), and a bovine growth hormone polyA signal. This transgene was injected into C57BL/6J mouse embryos. To establish founder line 25175, founder mice (F0) were bred to B6.R26-lacZ mutant mice (Gt(ROSA)26Sortm1Sor mutant mice backcrossed to C57BL/6N or C57BL/6J for at least 10 generations. CreERT2-positive::lacZ-positive transgenic mice (F1) were bred to C57BL/6 mice.
  • mutations:
  • Insertion
  • synonyms:
  • Pak7-Cre-ERT2-bGHpA line #25175,
  • Pak7-Cre-ERT2-bGHpA line #25175
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