Primary Identifier | MGI:5013582 | Allele Type | Transgenic |
Attribute String | Knockdown, Reporter | Gene | Tg(UBB-EmGFP/RNAi:Sarm1)#Yph |
Strain of Origin | C57BL/6J | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The transgene contains a human UBB promoter driving ubiquitous expression of a floxed DsRED*T3/stop cassette, emerald GFP (EmGFP) usptream of two different short hairpins targeting Sarm1, two polyadenylation sequences, and tandem cHS sequences. Cre-mediated recombination removed the DsRED*T3/stop cassette. Three lines were generated with lines 1 and 3 exhibiting higher EmGFP expression compared with line 2. The pound symbol is used when no line is specified and/or lines are pooled. |