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Allele : Pml<tm1(PML/RARA)Ley> promyelocytic leukemia; targeted mutation 1, Timothy J Ley

Primary Identifier  MGI:5014059 Allele Type  Targeted
Attribute String  Humanized sequence, Inserted expressed sequence, Null/knockout Gene  Pml
Transmission  Germline Strain of Origin  C57BL/6NTac-Tg(HBB-lacZ)ALey/Ley
Is Recombinase  false Is Wild Type  false
molecularNote  A cassette, which contains a floxed neo resistance gene with five stop codons in three frames and a fusion of human PML and RARA, was inserted into the 5' untranslated region. The absence of protein expression was confirmed by western blot analysis on spleen cells.
  • mutations:
  • Insertion
  • synonyms:
  • mPML-PRflox,
  • mPML-PRflox
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

7 Publication categories