| Primary Identifier | MGI:5014211 | Allele Type | Transgenic |
| Attribute String | Humanized sequence, Inducible, Inserted expressed sequence, Reporter, Transactivator | Gene | Tg(Gfap-rtTA,tetO-MAOB,-lacZ)1Jkan |
| Strain of Origin | C57BL/6 | Induced With | doxycycline/tetracycline |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | This transgene consists of 2 co-injected constructs. One encodes for a reverse tetracycline responsive transactivator with expression driven by a murine Gfap promoter. The second has a bidirectional tetracycline responsive promoter that drives expression of a lacZ reporter and a human MOAB cDNA. Several founders were generated and the line with the highest level of expression was used for analyses. Line 1 was generated. |
