| Primary Identifier | MGI:5050823 | Allele Type | Chemically induced (ENU) |
| Gene | Inpp5d | Strain of Origin | 129 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A T to C transition was found at nucleotide position 2099 (Genbank NM_010566) in ENU mutant mice. This should cause an isoleucine to threonine change at amino acid residue 641. An in-vitro 5'-phosphatase assay demonstrated reduced enzyme activity as compared to un-mutated controls. Protein levels were reduced in Western blots as were mRNA levels by qRT-PCR. |
