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Allele : Mitf<tm6Arnh> melanogenesis associated transcription factor; targeted mutation 6, Heinz Arnheiter

Primary Identifier  MGI:5050704 Allele Type  Targeted
Gene  Mitf Transmission  Germline
Strain of Origin  (C57BL/6N x 129S6/SvEvTac)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  The targeted mutation modified the splice donor for exon 2B so that it became non functional but did not modify any of the encoded amino acids. In addition, codon 73 was modified to encode for Asp. A floxed neomycin selection cassette was inserted as well. This allele forcibly includes exon 2B as it can no longer be alternatively spliced.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Mitf<mi-S-S73DNeo>,
  • Mitf<mi-S-S73DNeo>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories