Primary Identifier | MGI:5052342 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Clec10a |
Transmission | Germline | Strain of Origin | B6.Cg-Thy1<a> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | An FRT-flanked selection vector containing a neomycin resistance gene and a single 5' loxP site was inserted upstream of exon 2 of the Mgl2 gene and a second loxP site was inserted downstream of exon 10 of the Clec10a gene. The selection cassette and exons 2 through 10 of Mgl2 and all of the Clec10a gene were subsequently removed from properly targeted mice by crossing to transgenic mice carrying Tg(EIIa-cre)C5379Lmgd. |