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Allele : Tg(Eno2-PSEN2)2348Ykk transgene insertion 2348, Yong K Kim

Primary Identifier	MGI:5052116	Allele Type	Transgenic
Attribute String	Humanized sequence, Inserted expressed sequence	Gene	Tg(Eno2-PSEN2)2348Ykk
Strain of Origin	(C57BL/6 x DBA/2)F2	Is Recombinase	false
Is Wild Type	false

molecularNote

A 1.8kb fragment of the rat Eno2 promoter drives expression of a human PSEN2 cDNA. High levels of mRNA expression were detected in the brain. Expression in the liver, kidney and intestines were higher than in the brain.

mutations:
Insertion

synonyms:
NSE-hPS2w,
NSE-hPS2w

earliestPublication:
Hwang DY, et al. (2002) Alterations in behavior, amyloid beta-42, caspase-3, and Cox-2 in mutant PS2 transgenic mouse model of Alzheimer's disease. FASEB J 16(8):805-13

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

3 Publication categories

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