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Allele : Tg(tetO-MAP2K1)#Ahsa transgene insertion, AH Sawalha

Primary Identifier  MGI:5056483 Allele Type  Transgenic
Attribute String  Dominant negative, Inducible, Inserted expressed sequence Gene  Tg(tetO-MAP2K1)#Ahsa
Strain of Origin  C57BL/6 x (C57BL/6 x SJL)F1 Induced With  doxycycline/tetracycline
Is Recombinase  false Is Wild Type  false
molecularNote  A dominant-negative mutation of a human cDNA encoding S218A, S222A, and K97A amino acid residue substitutions was placed under the control of TRE2 (tetO) regulatory elements. The purified construct was then injected into nuclei of one-celled embryos.
  • mutations:
  • Insertion
  • synonyms:
  • TRE2-MEK,
  • TRE2-MEK
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories