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Allele : Gt(ROSA)26Sor<tm2(OVA/EGFP)Dwir> gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Dagmar Wirth

Primary Identifier  MGI:5056498 Allele Type  Targeted
Attribute String  Conditional ready, Inserted expressed sequence, Reporter, RMCE-ready Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  RMCE replaced the floxed luciferase gene in Gt(ROSA)26Sortm1Dwir with an inverted fusion protein of the hsp 73-capturing N-terminal viral J domain of SV40 T-Ag (cT77); 108-residue of the Ovalbumin fragment (aa 246-353 with a isoleucine to valine change at position 258) with well-characterized Kb- and Ad/b-binding epitopes (specifically recognized by OT-I or OT-II/D011 TCR), and the eGFP reporter. Cre-mediated recombination is required to achieve expression of the fusion protein.
  • mutations:
  • Insertion
  • synonyms:
  • ROSAOVA,
  • ROSAOVA
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories