Primary Identifier | MGI:6850125 | Allele Type | Targeted |
Attribute String | Modified isoform(s) | Gene | Adm |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A gene-targeting vector was generated containing the promoter and exon 1, intron 1, part of exon 2, part of exon 3, intron 3, and exon 4 of the Adm gene upstream of a BamH1 site and a neomycin resistance cassette. The finale allele lacks the coding sequence for the proadrenomedullin N-terminal 20 peptide. |