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Allele : Efnb2<tm3.1Henk> ephrin B2; targeted mutation 3.1, Mark Henkemeyer
Primary Identifier  MGI:5085271 Allele Type  Targeted
Gene  Efnb2 Transmission  Germline
Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+> Is Recombinase  false
Is Wild Type  false
molecularNote  The 6 tyrosines in the cytoplasmic domain were mutated to phenylalanine to prevent tyrosine phosphorylation, the GTC codon for valine in exon 5 was deleted, and a floxed neo cassette was inserted via homologous recombination. Cre mediated recombination removed the neo cassette.
  • mutations:
  • Insertion,
  • Intragenic deletion,
  • Nucleotide substitutions
  • synonyms:
  • ephrin-B2<6YFdeltaV>,
  • ephrin-B2<6YFdeltaV>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

11 Publication categories





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