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Allele : Tg(JPH3-GFP,-JPH3*)GXwy transgene insertion G, X William Yang

Primary Identifier  MGI:5052365 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(JPH3-GFP,-JPH3*)GXwy
Strain of Origin  FVB/N Is Recombinase  false
Is Wild Type  false
molecularNote  The human BAC (RP11-33A21) was modified to include a transcriptional stop sequence (GFP followed by a floxed pgk-neo cassette and a polyA signal) before exon 1 and an expanded CTG/CAG track of 120 repeats in exon 2A of JPH3. RT-PCR confirmed that expression of the sense strand CUG repeat is silenced but expression of the antisense CAG repeat is retained.
  • mutations:
  • Insertion
  • synonyms:
  • BAC-HDL2-STOP,
  • BAC-HDL2-STOP
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories