Primary Identifier | MGI:5056374 | Allele Type | Chemically induced (ENU) |
Gene | Casp3 | Strain of Origin | A/J |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Identified in an ENU screen and mapped to a 4 Mb interval on Chromosome 8 containing Casp3. A mutation two bases upstream of exon 3 results in splicing errors causing exon 3 splicing to be 4 nucleotides into the wild type exon or loss of exon 3 altogether. Both forms result in premature stop codons. |