Primary Identifier | MGI:5085782 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Cyfip2 |
Transmission | Germline | Strain of Origin | C57BL/6NTac |
Is Recombinase | false | Is Wild Type | false |
Project Collection | KOMP-Regeneron |
molecularNote | The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 30824bp between positions 46151630-46182453 of Chromosome 11 (Build GRCm39). The lacZ cassette replaced exons 2-5. QRT-PCR confirmed a 50% reduction in transcript expression in the hippocampus and cortex of heterozygotes. |