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Allele : Pou2f3<tm1Abek> POU domain, class 2, transcription factor 3; targeted mutation 1, Keiko Abe

Primary Identifier  MGI:5140071 Allele Type  Targeted
Attribute String  Null/knockout Gene  Pou2f3
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  An approximately 4 kb fragment, including exons 7 - 9 encoding for the POU homeodomain and a part of the POU?specific domain, was replaced with a tk-neo cassette via homologous recombination. In situ and immunohistochemical analysis indicated the expression of a truncated mRNA in a small population of basal cells and the absence of the a isoform of the protein in the taste buds of homozygous mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Skn-1a<->,
  • Skn-1a<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

27 Publication categories

Trail: Allele