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Allele : Tbx1<tm8.1Bld> T-box 1; targeted mutation 8.1, Antonio Baldini

Primary Identifier	MGI:5140346	Allele Type	Targeted
Gene	Tbx1	Transmission	Germline
Strain of Origin	129S7/SvEvBrd-Hprt1<b-m2>	Is Recombinase	false
Is Wild Type	false

molecularNote

The 2973 bp sequence upstream of and including the Fox binding site was replaced with a floxed Hprt selection cassette. Cre-mediated recombination removed the selection cassette. Reduced transcript expression was confirmed by RT-PCR.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

synonyms:
Tbx1<deltaFG>,
Tbx1<deltaFG>

earliestPublication:
Zhang Z, et al. (2010) Manipulation of endogenous regulatory elements and transgenic analyses of the Tbx1 gene. Mamm Genome 21(11-12):556-64

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

4 Publication categories

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