| Primary Identifier | MGI:5140704 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Epb41l3 |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | An FRT flanked neo cassette and a loxP site were inserted in intron 5. A second loxP site was inserted in intron 6. Exon 6 which encodes part of theFERM domain is thus flanked by loxP sites. Deletion of exon 6 by cre mediated excision also results in a frame shift creating a stop codon in exon 7. Both 145 and 125 kDa protein isoforms were lost as determined by immunoblotting. |
