Primary Identifier | MGI:5140722 | Allele Type | Targeted |
Gene | F2 | Transmission | Germline |
Strain of Origin | 129P2/OlaHsd | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Exon 14 was replaced with a modified exon 14 in which nucleotide substitutions result in the amino acid substitutions of alanine for tryptophan and glutamic acid at positions 215 and 217, respectively (W215A, E217A). An Hprt gene was inserted downstream of the modified exon. |