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Allele : Pdgfrb<tm14(Pdgfrb)Sor> platelet derived growth factor receptor, beta polypeptide; targeted mutation 14, Philippe Soriano

Primary Identifier  MGI:5140883 Allele Type  Targeted
Attribute String  Conditional ready, Constitutively active, Inserted expressed sequence, No functional change Gene  Pdgfrb
Transmission  Germline Strain of Origin  129S4/SvJaeSor
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 2 and 3 were replaced with a splice acceptor, floxed neo/stop cassette, and the mouse cDNA with nucleotide substitution(s) that results in the amino acid substitution of valine for aspartic acid at position 849 (D849V). This mutation is an activating mutation.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • PDGFRbeta<(S)K>,
  • PDGFRbeta<(S)K>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

11 Publication categories