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Allele : Cdk6<tm3.1Phin> cyclin dependent kinase 6; targeted mutation 3.1, Philip Hinds

Primary Identifier  MGI:5141515 Allele Type  Targeted
Gene  Cdk6 Transmission  Germline
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 1 was replaced with one in which nucleotide substitutions result in the amino acid substitution of methionine for lysine at position 43 (K43M). A floxed stop cassette downstream of the modified exon 1 that prevents expression was removed by cre-mediated recombination. The product is predicted to be an inactive kinase.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • Cdk6<K43M>,
  • Cdk6<K43M>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories