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Allele : Slc39a8<tm1.1Dwn> solute carrier family 39 (metal ion transporter), member 8; targeted mutation 1.1, Daniel W Nebert

Primary Identifier  MGI:5285694 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Slc39a8
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted 316bp downstream of exon 6 in intron 6. A loxP and Frt flanked neomycin selection cassette were inserted in intron 3. The neo selection cassette was subsequently removed by crossing to mice expressing flp recombinase. This left exons 4, 5, and 6 flanked by loxP sites. However, cre recombinase failed to excise the floxed exons in living mice although excision succeeded in cultured cells.
  • mutations:
  • Insertion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

5 Publication categories