Primary Identifier | MGI:5285550 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Htra1 |
Transmission | Germline | Strain of Origin | 129S4/SvJae |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Part of exon 1 including the ATG initiation codon was replaced with an IRES-lacZ reporter and neomycin-resistance cassette via homologous recombination. Northern blot and RT-PCR analysis confirmed the absence of expression in brains and retinas from homozygous mice |