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Allele : Cradd<tm1(KOMP)Mbp> CASP2 and RIPK1 domain containing adaptor with death domain; targeted mutation 1, Mouse Biology Program, UC Davis

Primary Identifier  MGI:5287724 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Cradd
Transmission  Cell Line Strain of Origin  C57BL/6N-A<tm1Brd>
Is Recombinase  false Is Wild Type  false
Project Collection  KOMP-CSD
molecularNote  The insertion of the L1L2_Bact_P cassette created a deletion of size 577 starting at position 95158434 and ending at position 95159011 of Chromosome 10 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories