| Primary Identifier | MGI:5287977 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Lmx1a |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A genomic fragment, including exons 1and 2, intron 1 and part of intron 2, was replaced with an EGFP gene and a floxed neo cassette via homologous recombination. In heterozygous mice EGFP expression recapitulates endogenous gene expression. Immunohistochemical analysis confirmed the absence of wild-type protein expression in the ventral midbrain of homozygous embryos at E11.5. |
