Primary Identifier | MGI:5288509 | Allele Type | Targeted |
Attribute String | Inserted expressed sequence, Null/knockout | Gene | Mapk14 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A cDNA for Mapk11 and a floxed neo cassette were inserted in frame after the ATG codon in exon 1 replacing the rest of exon 1 and part of intron 1. Cre mediated recombination removed the neo cassette. RT-PCR analysis confirmed the expression in all tissues examined (brain, liver, spleen, colon, heart, muscle, kidney, and liver). |