| Primary Identifier | MGI:5287872 | Allele Type | Transgenic |
| Attribute String | Recombinase | Gene | Tg(Tpbpa-cre,-EGFP)5Jcc |
| Strain of Origin | Not Specified | Is Recombinase | true |
| Is Wild Type | false |
| molecularNote | Transgenic mice were generated using a construct in which a cre recombinase-IRES-EGFP cassette was cloned downstream of the Tpbpa promoter. Three independent lines were obtained and all lines produced similar temporal and spatial expression patterns of cre-EGFP that correlated with those of the endogenous Tpbpa gene. Line 5 was used for further studies as it showed earliest onset of expression (around E8.0). Activity of cre recombinase in reporter assays also was detected by E8.0. |
