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Allele : Ptpmt1<tm1.2Jedi> protein tyrosine phosphatase, mitochondrial 1; targeted mutation 1.2, Jack E Dixon

Primary Identifier	MGI:5291922	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Ptpmt1
Transmission	Germline	Strain of Origin	(129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase	false	Is Wild Type	false

molecularNote

A loxP site was inserted upstream of exon 1. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 2. Cre-mediated recombination removed the neo cassette and exons 1 and 2.

mutations:
Intragenic deletion,
Insertion

cellLines:
Not Specified

earliestPublication:
Zhang J, et al. (2011) Mitochondrial phosphatase PTPMT1 is essential for cardiolipin biosynthesis. Cell Metab 13(6):690-700

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

4 Publication categories

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