| Primary Identifier | MGI:5292563 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Tet1 |
| Transmission | Germline | Strain of Origin | (C57BL/6 x 129S4/SvJae)F1 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A targeting vector containing a FRT site flanked neo cassette with a downstream loxP site was inserted upstream of exon 5. A second loxP site was inserted upstream of exon 4. Cre-mediated recombination removed the neo cassette and exon 4. The absence of protein expression was confirmed by western blot analysis on mouse embryonic fibroblasts. |
