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Allele : Smn1<tm2Cdid> survival motor neuron 1; targeted mutation 2, Christine DiDonato

Primary Identifier  MGI:5290070 Allele Type  Targeted
Attribute String  Hypomorph Gene  Smn1
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 7 was replaced with one in which a C to T transition at position 6 of this exon. A floxed pgk-neo selection cassette was inserted about 180 bp distal to exon 7 in the antisense orientation. Analysis of protein expression indicates very low levels of Smn1 and that this is a hypomorphic allele.
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • Smn<C-T-Neo>,
  • Smn<C-T-Neo>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories