|  Help  |  About  |  Contact Us

Allele : Gt(ROSA)26Sor<tm3(H1/tetO-RNAi:Mir143)Jcbr> gene trap ROSA 26, Philippe Soriano; targeted mutation 3, Jens C Bruning
Primary Identifier  MGI:5290071 Allele Type  Targeted
Attribute String  Inducible, Knockdown Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  (C57BL/6 x 129S6/SvEvTac)F1
Induced With  doxycycline/tetracycline Is Recombinase  false
Is Wild Type  false
molecularNote  A construct containing a short hairpin RNA targeting Mir143 driven by the H1/tetO operator fusion promoter followed by a CAG promoter driving expression of the tetR regulatory cassette was inserted into the locus by flp-mediated recombination via RMCE with Gt(ROSA)26Sortm1(CAG-flpe)Arte. Doxycycline-treatment is required to activate the expression of the shRNA.
  • mutations:
  • Insertion
  • synonyms:
  • miR-143<DOX>,
  • miR-143<DOX>
Paste the following link
Quick Links:
SummaryGenomePhenotypeOther
 
Quick Links:
SummaryGenomePhenotypeOther
 
Lists
This Allele isn't in any lists. Upload a list.

1 Feature

Genome

0 Expresses

1 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories





MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom