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Allele : Gt(ROSA)26Sor<tm3(H1/tetO-RNAi:Mir143)Jcbr> gene trap ROSA 26, Philippe Soriano; targeted mutation 3, Jens C Bruning
Primary Identifier  MGI:5290071 Allele Type  Targeted
Attribute String  Inducible, Knockdown Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  (C57BL/6 x 129S6/SvEvTac)F1
Induced With  doxycycline/tetracycline Is Recombinase  false
Is Wild Type  false
molecularNote  A construct containing a short hairpin RNA targeting Mir143 driven by the H1/tetO operator fusion promoter followed by a CAG promoter driving expression of the tetR regulatory cassette was inserted into the locus by flp-mediated recombination via RMCE with Gt(ROSA)26Sortm1(CAG-flpe)Arte. Doxycycline-treatment is required to activate the expression of the shRNA.
  • mutations:
  • Insertion
  • synonyms:
  • miR-143<DOX>,
  • miR-143<DOX>
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1 Feature

Trail: Allele

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1 Mutation Involves

Trail: Allele

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