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Allele : Gt(ROSA)26Sor<tm4(H1/tetO-RNAi:Mir145)Jcbr> gene trap ROSA 26, Philippe Soriano; targeted mutation 4, Jens C Bruning
Primary Identifier  MGI:5290084 Allele Type  Targeted
Attribute String  Inducible, Knockdown, RMCE-ready Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  (C57BL/6 x 129S6/SvEvTac)F1
Induced With  doxycycline/tetracycline Is Recombinase  false
Is Wild Type  false
molecularNote  A construct containing a short hairpin RNA targeting Mir145 driven by the H1/tetO operator fusion promoter followed by a CAG promoter driving expression of the tetR regulatory cassette was inserted into the locus via flp-mediated recombination using RMCE with Gt(ROSA)26Sortm1(CAG-flpe)Arte. Doxycycline-treatment is required to activate expression of the shRNA.
  • mutations:
  • Insertion
  • synonyms:
  • miR-145<DOX>,
  • miR-145<DOX>
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1 Feature

Genome

0 Expresses

1 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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0 Driven By

4 Publication categories





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