Primary Identifier | MGI:5291826 | Allele Type | Transgenic |
Attribute String | Recombinase | Gene | Tg(Pdgfrb-cre)35Vli |
Strain of Origin | FVB/N x B6;129S4-Gt(ROSA)26Sor<tm1Sor>/J | Is Recombinase | true |
Is Wild Type | false |
molecularNote | The transgenic construct contained a 4.8 kb fragment of Pdgfrb including the promoter and the first exon fused to a nuclear-targeted cre recombinase sequence. The construct was injected into fertilized oocytes. Founders were crossed to Gt(ROSA)26Sortm1Sor reporter mice to analyze cre activity in embryonic and adult tissues. Line 35 was used for further experiments. |