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Allele : Tmprss11d<tm1Bug> transmembrane protease, serine 11d; targeted mutation 1, Thomas H Bugge

Primary Identifier  MGI:5293641 Allele Type  Targeted
Attribute String  Inserted expressed sequence, Reporter Gene  Tmprss11d
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A MICER vector (MHPN265D14) was used to insert an inverted neo cassette, a TYR1-HPRT construct, and a genomic fragment containing exons 4 and 5, after exon 5 of the gene. This insertion introduces a frameshift mutation. RT-PCR analysis showed the expression of a mutant transcript containing the duplicated exons.
  • mutations:
  • Insertion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories