| Primary Identifier | MGI:5293667 | Allele Type | Targeted |
| Attribute String | Not Specified | Gene | Glra1 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A targeting construct was designed to insert a frt-flanked neomycin (neo) resistance cassette downstream of exon 8 of the glycine receptor, alpha 1 subunit (Glra1) gene. Nucleotide substitutions (ATG to CTA) introduced in exon 8 resulted in the amino acid mutation M287L. Flp-mediated recombination removed the neo cassette. |