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Allele : Cyld<tm1.1Mpa> CYLD lysine 63 deubiquitinase; targeted mutation 1.1, Manolis Pasparakis

Primary Identifier  MGI:5293377 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Cyld
Transmission  Germline Strain of Origin  B6.Cg-Thy1<a>
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted upstream of exon 17. A STOP and FRT-flanked neo cassette with a 3' loxP site followed by a modified exon 17, in which nucleotide substitution results in the amino acid substitution of a stop codon at position 932, was inserted downstream of the endogenous exon 17. The predicted protein is truncated at position 932 (delta932). Flp-mediated recombination removed the neo cassette.
  • mutations:
  • Insertion
  • synonyms:
  • CYLDDelta932<FL>,
  • CYLDDelta932<FL>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

8 Publication categories