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Allele : Gt(ROSA)26Sor<tm1(H1/tetO-RNAi:Pion)Pggd> gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Paul Greengard
Primary Identifier  MGI:5294908 Allele Type  Targeted
Attribute String  Inducible, Knockdown, RMCE-ready Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  (C57BL/6 x 129S6/SvEvTac)F1
Induced With  doxycycline/tetracycline Is Recombinase  false
Is Wild Type  false
molecularNote  The short hairpin RNA (shRNA) against Pion (5'-TCCCGGAACTCCATGATTGACAAATTTCAAGAGAATTTGTCAATCATGGAGTTCCTTTTTA-3') was inserted into the locus via RMCE with Gt(ROSA)26Sortm1(CAG-flpe)Arte. The shRNA sequence is under the regulation of the tetO operator and a codon optimized tet repressor (itetR) under the control of a CAG promoter.
  • mutations:
  • Insertion
  • synonyms:
  • GSAP-RNAi,
  • GSAP-RNAi
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1 Feature

Genome

0 Expresses

1 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories





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