Primary Identifier | MGI:5295192 | Allele Type | Targeted |
Gene | Zeb1 | Transmission | Germline |
Strain of Origin | B6.Cg-Thy1<a> | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A single nucleotide G to A substitution located 181 bp downstream of Zeb1 exon 1 and 12 bp downstream of exon 1 of the predicted gene Gm10125, a loxP site, and IRES-lacZ cassette, and a floxed inverted pgk-neo cassette were inserted via homologous recombination. Cre mediated recombination removed the IRES-lacZ and pgk-neo cassettes. This mutation is designed to duplicate the one found in Zeb1Tw mice |