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Allele : S1pr1<tm1.1Cys> sphingosine-1-phosphate receptor 1; targeted mutation 1.1, Jason G Cyster
Primary Identifier  MGI:5295051 Allele Type  Targeted
Gene  S1pr1 Transmission  Germline
Strain of Origin  129P2/OlaHsd Is Recombinase  false
Is Wild Type  false
molecularNote  Nucleotide substitutions replaced the threonine and serines in the TxxSS motif in the last 12 amino acids of the sequence with alanines (p.T371A and p.(S374_S375delinsAA)). A floxP site flanked neomycin resistance gene cassette was inserted into the 3' UTR. Subsequent cre-mediated recombination removed the neo cassette.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • S1PR1<TSS>,
  • S1PR1<TSS>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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1 Carried By

Trail: Allele

0 Driven By

6 Publication categories

Trail: Allele




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