| Primary Identifier | MGI:5295371 | Allele Type | Targeted |
| Gene | Lrrk2 | Transmission | Germline |
| Strain of Origin | BALB/c | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Exon 41 was replaced with a floxed modified exon 41 with nucleotide substitutions (GAC to TCC) that result in the amino acid substitution of serine for aspartic acid at position 1994 (D1994S). An FRT-flanked neo cassette inserted downstream of the modified exon 41 was removed by flp-mediated recombination. The predicted protein is kinase dead. |
