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Allele : Nkx2-2<tm2.1Suss> NK2 homeobox 2; targeted mutation 2.1, Lori Sussel
Primary Identifier  MGI:5297810 Allele Type  Targeted
Attribute String  RMCE-ready Gene  Nkx2-2
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  Recombination mediated cassette exchange (RMCE) into Nkx2-2tm1Suss inserted nucleotide substitutions that result in several amino acid substitutions in the tinman (TN) domain (TGFSVKDILDLP to TGFAAAAIVDLP). An FRT-flanked neo cassette used for selection was removed by flp-mediated recombination.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Nkx2.2<TNmut>,
  • Nkx2.2<TNmut>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories





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