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Allele : Gt(ROSA)26Sor<tm4(tetO-RNAi:T)Bgh> gene trap ROSA 26, Philippe Soriano; targeted mutation 4, Bernhard G Herrmann
Primary Identifier  MGI:5297159 Allele Type  Targeted
Attribute String  Inducible, Knockdown, RMCE-ready Gene  Gt(ROSA)26Sor
Transmission  Chimeric Strain of Origin  Not Specified
Induced With  doxycycline/tetracycline Is Recombinase  false
Is Wild Type  false
description  ES cell lines = C57BL/6 and G4.
molecularNote  Recombinase mediated cassette exchange was used to insert two short hairpin RNAi specific for the Brachyury (T) gene under the combined control of tetO and CAG followed by a PGK promoter into the Gt(ROSA)26Sortm1Bgh allele. The tetracycline silencer prevents expression of the shRNAi until mice are treated with doxycycline.
  • mutations:
  • Insertion
  • synonyms:
  • KD1-T,
  • KD1-T
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1 Mutation Involves

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