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Allele : Tg(Nphs1-Ptgs2)14Rhrs transgene insertion 14, Raymond Harris

Primary Identifier	MGI:5301702	Allele Type	Transgenic
Attribute String	Inserted expressed sequence	Gene	Tg(Nphs1-Ptgs2)14Rhrs
Strain of Origin	(C57BL/6 x DBA/2)F1	Is Recombinase	false
Is Wild Type	false

molecularNote

The mouse Ptgs2, prostaglandin-endoperoxide synthase 2 (Cox-2), gene was placed under the control of a 8.5-kb fragment containing the promoter of the mouse Nphs1, nephrosis 1 homolog.

mutations:
Insertion

synonyms:
Nephrin-COX-2-Tg,
Cox-2 Tg,
Cox-2 Tg,
Nephrin-COX-2-Tg

earliestPublication:
Jo YI, et al. (2007) Puromycin induces reversible proteinuric injury in transgenic mice expressing cyclooxygenase-2 in podocytes. Nephron Exp Nephrol 107(3):e87-94

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

5 Publication categories

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